The ConSurf Server
SERVER FOR THE IDENTIFICATION OF FUNCTIONAL REGIONS IN BIOPOLYMERS
ConSurf Job Status Page - FINISHEDGo To The Results
PDB ID: 2pol
Chain identifier: A
Neighbor Joining with ML distance
Method of Calculation: Bayesian
Model of substitution for proteins: Best fit
Multiple Sequence Alignment is built using MAFFT
The Homologues are collected from UNIREF90
Homolog search algorithm: HMMER
HMMER E-value: 0.0001
No. of HMMER Iterations: 1
Maximal %ID Between Sequences : 95
Minimal %ID For Homologs : 35
150 sequences that sample the list of homologues to the query.
Extract sequence from PDB file
Find sequence homologs
Remove redundant and unrelated sequences
Select best evolutionary model
Calculate conservation scores
Project conservation scores onto the molecule
There are 3775 HMMER hits. 3712 of them are unique, including the query.
The calculation is performed on a sample of 150 sequences that represent the list of homologues to the query.
Here is the list of sequences that produced significant alignments, but were not chosen as hits.
The best evolutionary model was selected to be: LG. (details).