- Extract sequence from PDB file
- Select best evolutionary model
- Calculate conservation scores
- Project conservation scores onto the molecule
Running Messages:
- There are 1457 HMMER hits. 1438 of them are unique, including the query.
The calculation is performed on a sample of 150 sequences that represent the list of homologues to the query.
- Click here if you wish to view the list of sequences which produced significant alignments, but were not chosen as hits.
- The best evolutionary model was selected to be: LG. See details here
Final Results
- View ConSurf results with FirstGlance in Jmol [load results using color-blind friendly scale here]
Note: FirstGlance version was updated. In case you can't see the molecule and get warnings, press OK and afterwards press Ctrl+F5 keys to reload the new version. You can read more about the issue here.
- Download all ConSurf outputs in a click!
PDB Files
Create high resolution figures
Sequence Data
- HMMER output (HMMER hits with E-values and pairwise alignments)
- Sequences Used (displayed in FASTA format, linked to sequence data-base)
Alignment
Alignment details
The average number of replacements between any two sequences in the alignment;
A distance of 0.01 means that on average, the expected replacement for every 100 positions is 1.
Average pairwise distance : 1.11182
Lower bound : 0.116688
Upper bound : 1.87958
Phylogenetic Tree
Project ConSurf scores on the protein most probable assembly
- View ConSurf results projected on PISA first model with FirstGlance in Jmol [load results using color-blind friendly scale here]
Note: FirstGlance version was updated. In case you can't see the molecule and get warnings, press OK and afterwards press Ctrl+F5 keys to reload the new version. You can read more about the issue here.
RasMol Coloring Scripts
PDB Files
Create a high resolution figures